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1 Strip = 10 Tablets
NIPRO JMI PharmaProduct Description
Lijenta M contains the combination of Linagliptin and Metformin, an oral antihyperglycemic treatment used to improve glycemic control in adults with type 2 diabetes mellitus. This dual-action therapy leverages two distinct mechanisms: Linagliptin, a DPP-4 inhibitor, works by increasing the levels of incretin hormones that stimulate insulin release and decrease glucagon production, while Metformin, a biguanide, primarily reduces hepatic glucose production and improves insulin sensitivity in peripheral tissues. By addressing multiple physiological defects of the disease, this combination helps lower both fasting and postprandial blood glucose levels more effectively than either drug alone. It is particularly valued in clinical practice because Linagliptin is primarily excreted through the bile and gut, making it a safer option for patients with varying degrees of renal impairment, although the Metformin component still requires careful monitoring of kidney function.
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