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1 Strip = 15 Tablets
Synovia Pharma PLC.Product Description
Glimepiride is a potent, third-generation sulfonylurea used in the management of type 2 diabetes mellitus to improve glycemic control. It exerts its hypoglycemic effect primarily by stimulating the release of insulin from pancreatic beta cells through the inhibition of ATP-sensitive potassium channels, which leads to cell depolarization and calcium influx. Unlike earlier sulfonylureas, glimepiride is noted for its rapid onset of action and a lower risk of long-term hyperinsulinemia, as it associates and dissociates more quickly with its specific binding protein. It is typically administered once daily and is often favored for its dual mechanism, which may include enhancing peripheral insulin sensitivity in muscle and fat tissues. The most significant clinical considerations during treatment include the risk of hypoglycemia and weight gain, necessitating careful dose titration and patient education regarding meal timing.
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