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15 gm tube
The IBN SINA PharmaceuticalProduct Description
Indications
This preparation cream is indicated in the treatment of-
Mixed and complicated Fungal, Protozoal & Bacterial infections,
Mild to moderate vaginitis,
Candidiasis and trichomoniasis,
Pruritus vulvae,
Dermatitis,
Eczema,
Genito-urinary infections.
Composition
Each gram cream contains-
Clobetasol Propionate USP 0.50 mg
Ofloxacin USP 7.50 mg
Ornidazole INN 20 mg
Terbinafine Hydrochloride BP 10 mg
Pharmacology
This cream is a combination cream which exhibits anti-bacterial, anti-fungal, anti-protozoal & anti-inflammatory actions. Ofloxacin is a broad-spectrum antibiotic that acts against many gram-positive & gram-negative bacteria. Ornidazole belongs to the nitroimidazole group of antibiotics and is used to treat amoeba and trichomonas infections. Terbinafine is an Allylamine antifungal that inhibits biosynthesis of Ergosterol (an essential components if fungal cell membrane) via inhibition of Squalene Epoxidase enzyme causing fungal cell death. Clobetasol is a potent corticosteroid which exhibits anti-inflammatory, anti-pruritic and vasoconstrictive properties.
Dosage & Administration
Apply by gently rubbing onto the affected area twice daily.
Interaction
No hazardous interactions have been reported.
Contraindications
Contraindicated in patients hypersensitive to any of the components of the formulation.
Side Effects
Burning, itching, irritation, dry skin
Pregnancy & Lactation
The safe use of this preparation during pregnancy & lactation has not been established.
Precautions & Warnings
Do not shallow. For external use only
Therapeutic Class
4-Quinolone preparations, Clobetasol / Clobetasone & Combined Preparations
Storage Conditions
Store below 30°C. keep away from light and out of the reach of children. Do not freeze.
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